D-penicillamine induced degenerative dermopathy
نویسندگان
چکیده
منابع مشابه
A case of penicillamine-induced dermopathy.
INTRODUCTION We describe an interesting patient with penicillamine-induced dermopathy. CLINICAL PICTURE A 49-year-old woman presented with a 1-year history of recurrent haemorrhagic blisters, milia and purpura over both her elbows, while on long-term penicillamine therapy (1.5 g daily) for Wilson's disease. Histologically, dermal elastin fibres were markedly reduced in the affected areas, con...
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Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigabilit...
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Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
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To the Editor: Elastosis perforans serpiginosa (EPS) is part of different kinds of perforating diseases that are dependent on factors such as idiopathic, reactive, or drug induced. We report here a case of a patient who presented with multiple reddish‐brown keratinized papules coalescing to form serpiginous plaques in the anterior and posterior of the neck, which was found to be typical D‐penic...
متن کاملD-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist.
The case of a 57-year-old woman with rheumatoid arthritis is presented to illustrate the rare occurrence of a myasthenic syndrome induced by D-penicillamine, which led to prolonged (5.25-h) postoperative apnoea necessitating artificial ventilation.
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2015
ISSN: 0019-5154
DOI: 10.4103/0019-5154.160498